Availability of Copper to Sheep from Cu-64 Labeled Inorganic Compounds

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Abstract
Blood and plasma concentrations after oral administration were greater (P<0.05) from the chloride source than from the sulfate, nitrate or cupric oxide needles sources of Cu~64. Cumulative fecal or urinary excretions from the chloride, nitrate or sulfate forms did not differ but exceeded (P<0.01) excretions from the cupric oxide needles. In a subsequent experiment, the blood and plasma concentrations were significantly greater from the oral carbonate source than from the oxide sources. Cumulative fecal excretion from the cupric oxide powder was significantly greater than from the cupric carbonate, while cumulative urine excretion from the cupric carbonate was significantly greater than from the other sources. Intravenous injection of radioactive copper-64 in the form of the chloride, nitrate or sulfate showed cumulative excretion in the urine to be greater (P<0.01) from the chloride source than from the nitrate or sulfate. Copyright © . .

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