Apparent predisposition to systemic lupus erythematosus in Chinese patients in West Malaysia.

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Abstract
Patients (175) fulfilled the American Rheumatism Association criteria for systemic lupus erythematosus [SLE]. This diagnosis was made significantly more frequently in Chinese patients than in other races. SLE is more often reported from Chinese communities in Asia than from India and tropical Africa. There may be a lower susceptibility to autoimmune disease in black Africans than the suspected increased susceptibility in their American Negro and West Indian descendants. A careful study of racial and geographical factors in autoimmune disease should help explain interaction between the host and his environment which results in autoimmune disease.