Spontaneous absolute asymmetric synthesis in the presence of achiral silica gel in conjunction with asymmetric autocatalysis
- 1 January 2006
- Vol. 18 (7) , 479-482
- https://doi.org/10.1002/chir.20273
Abstract
An enantiomerically enriched pyrimidyl alkanol with either S or R configurations was obtained stochastically from the reaction between pyrimidine-5-carbaldehyde and diisopropylzinc in the presence of achiral silica gel in conjunction with asymmetric autocatalysis with amplification of chirality. Chirality 18:479–482, 2006.Keywords
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