The Inflammasome — A Linebacker of Innate Defense
- 17 August 2006
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 355 (7) , 730-732
- https://doi.org/10.1056/nejmcibr063500
Abstract
The cryopyrin gene, previously shown to be mutated in patients with periodic-fever syndrome, is critical in the innate immune response to some bacterial infections and to the inflammation that occurs after exposure to the crystalline material found in the joints of people with gout and pseudogout.Keywords
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