Evidence for a noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat

This publication has 25 references indexed in Scilit:

• The role of descending noradrenergic systems in regulation of nociception: the effects of intrathecally administeredt α-adrenoceptor antagonists and clonidine
  Pain, 1990
• Synergy between the antinociceptive effects of intrathecal clonidine and systemic morphine in the rat
  Pain, 1988
• Monoamine and opioid interactions in spinal analgesia and tolerance
  Pharmacology Biochemistry and Behavior, 1987
• Evidence that adjuvant arthritis in the rat is associated with chronic pain
  Pain, 1987
• Increased norepinephrine and uric acid levels in the spinal cord of arthritic rats
  Brain Research, 1986
• Yohimbine both increases and decreases nociceptive thresholds in rats: Evaluation of the dose-response relationship
  Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1983
• Alterations in nociceptirve threshold and morphine-induced analgesia produced by intrathecally administered amine antagonists
  Brain Research, 1981
• Ethical standards for investigations of experimental pain in animals
  Pain, 1980
• Pain modulation by adrenergic agents and morphine as measured by three pain tests
  Life Sciences, 1980
• Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine
  Nature, 1978