The SHAPES strategy: an NMR-based approach for lead generation in drug discovery

• 1 October 1999
• journal article
• Published by Elsevier in Chemistry & Biology
• Vol. 6  (10) , 755-769
• https://doi.org/10.1016/s1074-5521(00)80022-8

Abstract

Keywords

• SCREENING
• SHAPES
• DRUG DESIGN
• LIBRARY
• NMR
• VIRTUAL SCREENING
• DRUG TARGETING
• MOLECULAR WEIGHT
• NUCLEAR OVERHAUSER EFFECT
• HIGH THROUGHPUT SCREENING
• COMBINATORIAL CHEMISTRY
• DRUG DISCOVERY
• NUCLEAR MAGNETIC RESONANCE