Risk of Amyotrophic Lateral Sclerosis and History of Physical Activity
Open Access
- 1 February 1998
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 55 (2) , 201-206
- https://doi.org/10.1001/archneur.55.2.201
Abstract
AMYOTROPHIC LATERAL sclerosis (ALS) is a devastating disease for which a satisfactory treatment is lacking. Some interplay among immutable host factors and modifiable environmental and behavioral factors likely determines who will develop ALS. Identification of causative risk factors could provide clues about its pathophysiological features and prevention. Several epidemiological studies of ALS have suggested that vigorous physical activity, both at the workplace and during leisure time, may be such a risk factor1,2 although a recent case-control study did not.3Keywords
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