Stereospecific synthesis of a novel azetido[2,1-c][1,4]-benzodiazepine (ABD) ring system with DNA recognition potential
- 18 August 1997
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 38 (33) , 5839-5842
- https://doi.org/10.1016/s0040-4039(97)01297-5
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Inhibition of Bacteriophage T7 RNA Polymerase in Vitro Transcription by DNA-Binding Pyrrolo[2,1-c][1,4]benzodiazepinesBiochemistry, 1997
- Synthesis of Sequence-Selective C8-Linked Pyrrolo[2,1-c][1,4]benzodiazepine DNA Interstrand Cross-Linking AgentsThe Journal of Organic Chemistry, 1996
- Synthesis of DNA-Interactive Pyrrolo[2,1-c][1,4]benzodiazepinesChemical Reviews, 1994
- A quantitative assay to measure the relative DNA-binding affinity of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour antibiotics based on the inhibition of restriction endonucleaseBamhINucleic Acids Research, 1993
- Rational design of a highly efficient irreversible DNA interstrand cross-linking agent based on the pyrrolobenzodiazepine ring systemJournal of the American Chemical Society, 1992
- Effect of linker length on DNA-binding affinity, cross-linking efficiency and cytotoxicity of C8-linked pyrrolobenzodiazepine dimersJournal of the Chemical Society, Chemical Communications, 1992
- DNA and associated targets for drug designJournal of Medicinal Chemistry, 1989
- DNA as a target for drug actionTrends in Pharmacological Sciences, 1988
- Pyrrolo[1,4]benzodiazepine antitumor antibiotics: relationship of DNA alkylation and sequence specificity to the biological activity of natural and synthetic compoundsChemical Research in Toxicology, 1988
- DNA sequence specificity of the pyrrolo[1,4]benzodiazepine antitumor antibiotics. Methidiumpropyl-EDTA-iron(II) footprinting analysis of DNA binding sites for anthramycin and related drugsBiochemistry, 1986