Abstract
Although a combined German—Czech experience encompassing nearly 2000 cases of ulcerative colitis is said to yield only three instances of secondary colonic cancer,1 Anglo-American experience unequivocally identifies ulcerative colitis as one of the conditions that predispose to cancer of the colon. Susceptibility to neoplastic degeneration increases with the duration of ulcerative colitis, and a popular ballpark figure is that colonic cancer develops in 10 per cent of patients who have ulcerative colitis for over 10 years. Though mnemonically convenient, these figures express an oversimplification.Irrespective of the duration of the disease, the danger of neoplastic change is greater when ulcerative . . .

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