Inhibition of 5?-nucleotidase by concanavalin A: Evidence for localization on the outer surface of the plasma membrane

Abstract
5′-Nucleotidase activity of rat liver plasma membrane is markedly inhibited by concanavalin A. Taken together with a unilateral pattern of labelling of concanavalin A binding sites with hemocyanin, the results indicate that an allosteric site of the enzyme is at the outer surface of the membrane.