Cytoplasmic pH in cultured porcine thyroid cells: alkalinization by Ca2+
- 1 September 1989
- journal article
- research article
- Published by Bioscientifica in Journal of Molecular Endocrinology
- Vol. 3 (2) , 163-166
- https://doi.org/10.1677/jme.0.0030163
Abstract
The role of calcium in cytoplasmic pH (pHi) changes was studied using 2′,7′-bis(2-carboxyethyl)-5-(and 6-)carboxyfluorescein, an internalized fluorescent pH indicator, in cultured porcine thyroid cells. The Ca2+ ionophores A23187 and ionomycin stimulated thyroid cell alkalinization. An increase in cytoplasmic free calcium resulted in activation of Na+/H+ exchange which alkalinized the cells.This publication has 12 references indexed in Scilit:
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