Stem Cell Replacement in Normal Thymus Grafts.
- 1 March 1964
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 115 (3) , 731-735
- https://doi.org/10.3181/00379727-115-29022
Abstract
After initial death of most donor lymphocytes in AKR thymus grafts in normal (AKRXT6)F1 mice, there was a temporary period during which active proliferation of surviving donor lymphocytes occurred. This population of dividing lymphocytes in the thymus grafts was subsequently completely replaced by host-type cells. The results suggest that thymic lymphoid stem cells are continuously replaced by cells entering the thymus from the circulation.Keywords
This publication has 2 references indexed in Scilit:
- THE AUTONOMOUS BEHAVIOUR OF NORMAL THYMUS GRAFTSImmunology & Cell Biology, 1963
- Thymus Specificity in Lethally Irradiated Mice Treated with Rat Bone MarrowExperimental Biology and Medicine, 1957