Characterizing the Effects of Caspofungin on Candida albicans , Candida parapsilosis , and Candida glabrata Isolates by Simultaneous Time-Kill and Postantifungal-Effect Experiments
- 1 July 2006
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 50 (7) , 2569-2572
- https://doi.org/10.1128/aac.00291-06
Abstract
We measured time-kills and postantifungal effects (PAFEs) of caspofungin against Candida albicans, C. parapsilosis, and C. glabrata isolates. One-hour exposure to caspofungin during PAFE experiments accounted for the majority of killing during time-kill experiments. Regrowth of all isolates was inhibited for at least 24 h following drug washout.Keywords
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