Cellular Response to Partial Hepatectomy

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Abstract
A study of hepatic regeneration in rats was carried out to see whether the stimulus of partial hepatectomy promotes proliferation of parenchymal liver cells or, in analogy with red cell regeneration, promotes the differentiation of stem cells to new hepatic parenchymal cells. By labelling a large proportion of hepatic cells with tritiated thymidine, it was shown that the labelled cells rather than the presumably unlabelled stem cells were responsible for hepatic regeneration following partial hepatectomy.

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