Monitoring Accumulating Data in a Clinical Trial
- 1 December 1989
- journal article
- research article
- Published by JSTOR
- Vol. 45 (4) , 1197-1211
- https://doi.org/10.2307/2531771
Abstract
A clinical trial is monitored for efficacy or safety; the variable of interest is death or a similarly serious event. The probability that one therapy has a greater mortality rate than the other is calculated ad libitum during the trial. Adjustments are made for differing patients'' prognoses and for survival times.This publication has 2 references indexed in Scilit:
- One-Sided Sequential Stopping Boundaries for Clinical Trials: A Decision- Theoretic ApproachPublished by JSTOR ,1988
- Bayesian statistical inference for psychological research.Psychological Review, 1963