Facile Synthesis of (E)-4-Aryl-2-Methyl-3-Butenoic Acids and Their Methyl Esters by the Condensation of Tiglic Acid Dianion with Arynes
- 1 March 1996
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 26 (5) , 963-971
- https://doi.org/10.1080/00397919608003700
Abstract
The condensation of various arynes with tiglic acid dianion yields (E)-4-aryl-2-methyl-3-butenoic acids exclusively, after proton quench. These acids were characterized as their methyl esters, which were prepared by treating the acids with diazomethane.Keywords
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