RAT EXPERIMENT IN A 22-DAY FLIGHT OF COSMOS-605 BIOSATELLITE (OBJECTIVES AND METHODS)

  • 1 January 1976
    • journal article
    • research article
    • Vol. 10  (3) , 9-14
Abstract
In 1974, a rat experiment was carried out onboard the Cosmos-605 biosatellite. Inflight Wistar rats were kept unrestrained in small cages equipped with a feeder, water supply, light source and a ventilation device. The state of the animals was assessed with respect to their motor activity. The flight experiment was preceded by a number of preparatory runs and testings that were completed with an end-to-end experiment in a biosatellite mockup. The flight experiment was paralleled by the ground-based synchronized experiment which simulated the flight profile. Rats were selected and trained during a month''s observation. Postflight rats were exposed to clinical, physiological, morphological, cytochemical and biochemical investigations. Tissue examinations were performed on the 2nd-3rd day (20 rats) and 26th-27th day (12 rats) after flight. Four rats were kept to study remote aftereffects.

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