Is One Set of Sextant Biopsies Enough to Rule Out Prostate Cancer? Influence of Transition and Total Prostate Volumes on Prostate Cancer Yield
- 1 January 2000
- journal article
- research article
- Published by Elsevier in European Urology
- Vol. 38 (2) , 218-224
- https://doi.org/10.1159/000020282
Abstract
Purpose: Although the sextant biopsy technique has been widely used, concern has arisen that this method may not include an adequate sampling of the prostate, especially for large prostate volumes. We conducted a multicenter study in patients with PSA levels 3, p3, p3, respectively, provided the best combination of sensitivity and specificity for discriminating between patients diagnosed with PCa after the first from those diagnosed after a second set. Conclusion: In patients with total prostate volume >45 cm3 and TZ >22.5 cm3, a single set of sextant biopsies may not be sufficient to rule out PCa. In these patients, a repeat biopsy should be considered in case of a negative first biopsy.Keywords
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