Direct Activation of Cystic Fibrosis Transmembrane Conductance Regulator Channels by 8-Cyclopentyl-1,3-dipropylxanthine (CPX) and 1,3-Diallyl-8-cyclohexylxanthine (DAX)
Open Access
- 1 March 1998
- journal article
- Published by Elsevier
- Vol. 273 (10) , 5727-5734
- https://doi.org/10.1074/jbc.273.10.5727
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- The Nucleotide Binding Folds of the Cystic Fibrosis Transmembrane Conductance Regulator Are Extracellularly AccessibleBiochemistry, 1997
- Cystic Fibrosis Transmembrane Conductance Regulator: The First Nucleotide Binding Fold Targets the Membrane with Retention of Its ATP Binding FunctionBiochemistry, 1997
- Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segmentBiophysical Journal, 1996
- Phosphorylation-dependent Block of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel by Exogenous R Domain ProteinPublished by Elsevier ,1996
- Glycerol Reverses the Misfolding Phenotype of the Most Common Cystic Fibrosis MutationJournal of Biological Chemistry, 1996
- Intracellular Loop between Transmembrane Segments IV and V of Cystic Fibrosis Transmembrane Conductance Regulator Is Involved in Regulation of Chloride Channel Conductance StatePublished by Elsevier ,1995
- A1 Receptor Antagonist 8-Cyclopentyl-1,3-dipropylxanthine Selectively Activates Chloride Efflux from Human Epithelial and Mouse Fibroblast Cell Lines Expressing the Cystic Fibrosis Transmembrane Regulator .DELTA.F508 MutationBiochemistry, 1995
- Stimulation by Alkylxanthines of Chloride Efflux in CFPAC-1 Cells Does Not Involve A1 Adenosine ReceptorsBiochemistry, 1995
- ATP alters current fluctuations of cystic fibrosis transmembrane conductance regulator: evidence for a three-state activation mechanism.The Journal of general physiology, 1994
- Cl - Channels in CF: Lack of Activation by Protein Kinase C and cAMP-Dependent Protein KinaseScience, 1989