The v? chain of fetal hemoglobin of the orangutan
- 1 December 1978
- journal article
- research article
- Published by Springer Nature in Biochemical Genetics
- Vol. 16 (11-12) , 1203-1205
- https://doi.org/10.1007/bf00484540
Abstract
Previous studies suggested that orangutans have nonallelic structural genes for their γ chains, because either a threonyl or an alanyl residue may occupy position 135. Further investigation has now detected that position 75 may have either an isoleucyl or a valyl residue. From available evidence, the isoleucyl and threonyl residues are in one chain and the valyl and alanyl in the other. Orangutans appear to be homozygous for the two types of nonallelic genes.This publication has 5 references indexed in Scilit:
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- Significance of a new type of human fetal hemoglobin carrying a replacement isoleucine ? threonine at position 75 (E 19) of the ? chainHuman Genetics, 1976
- Search for nonallelic structural genes for ?-chains of fetal hemoglobin in some primatesBiochemical Genetics, 1973
- Chimpanzee foetal haemoglobin: Structure and heterogeneity of the γ chainBiochimica et Biophysica Acta (BBA) - Protein Structure, 1971
- Evidence for multiple structural genes for the gamma chain of human fetal hemoglobin.Proceedings of the National Academy of Sciences, 1968