A Simple Method for the Synthesis of Nβ-Glycosylated-Asparagine and -Glutamine Derivatives

Abstract
N β-Glycosylated-asparagine and -glutamine derivatives, which are useful precursors for the synthesis of N-glucopeptides and their analogs, were obtained in good yields by the reaction of a glycosyl azide and an N α-protected-aspartic/glutamic acid α-monoester in the presence of trialkylphosphine at low temperature.

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