Ionic Liquid Acceleration of Solid-Phase Suzuki−Miyaura Cross-Coupling Reactions

9 August 2002

journal article
Published by American Chemical Society (ACS) in Organic Letters

Vol. 4 (18) , 3071-3073
https://doi.org/10.1021/ol0263292

Abstract

[reaction: see text] Room-temperature ionic liquids promote various transition metal-catalyzed reactions in the solution phase. Here, for the first time, we show that these effects are translatable to solid-phase reactions. The Suzuki-Miyaura cross-coupling of 4-iodophenol immobilized on polystyrene-Wang resin with various arylboronic acids was significantly accelerated by the ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF(4)(-)]).

Keywords

This publication has 2 references indexed in Scilit:

Statistical intelligence: effective analysis of high-density microarray data
Drug Discovery Today, 2002
In Situ Formation of Mixed Phosphine−Imidazolylidene Palladium Complexes in Room-Temperature Ionic Liquids
Organometallics, 2001