Abstract
Animal models [male or female hamster flank organ] for trials of anti-seborrheic drugs [ethinyl estradiol, diethylstilbestrol, promestriene, ethyl-1-hydroxy-5(hydroxy-4-phenyl)-2-methyl-3-indole CM4727, clofibrate, s-carboxy methyl-L-cysteine, eicosa tetrynoic acid and progesterone] do not adequately predict the effectiveness of the drugs in man.