Brief Communication: B-Cell Origin of Hamster Lymphoid Tumors Induced by Simian Virus 40
- 1 January 1975
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 54 (1) , 269-270
- https://doi.org/10.1093/jnci/54.1.269
Abstract
Two lymphoid neoplasms induced by simian virus 40 (SV40) in Syrian hamsters were analyzed for lymphocyte characteristics. The lymphocytes from both tumors contained membrane-bound Ig that was exclusively of 7Sγ2 class. Furthermore, neither lymphoid tumor had a complement receptor. Thus both tumors originated from a particular B-cell population, which suggests that this B-cell type is associated with an SV40 receptor.Keywords
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