Plasma 17α-Hydroxyprogesterone in Spironolactone-Treated Hypertensives
- 1 June 1977
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 44 (6) , 1200-1202
- https://doi.org/10.1210/jcem-44-6-1200
Abstract
When measured by a specific radioassay method which excludes drug interference, plasma 17.alpha.-hydroxyprogesterone levels were similar in spironolactone treated hypertensives, in untreated hypertensives and in normotensive volunteers. No in vivo evidence for a significant inhibitory effect of spironolactone on adrenal 11.beta., 17.alpha. and 21 hydroxylases was uncovered.This publication has 0 references indexed in Scilit: