Increased Atherosclerosis in Hyperlipidemic Mice With Inactivation of ABCA1 in Macrophages
Top Cited Papers
- 1 April 2002
- journal article
- research article
- Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology
- Vol. 22 (4) , 630-637
- https://doi.org/10.1161/01.atv.0000014804.35824.da
Abstract
The ATP-binding cassette transporter A1 (ABCA1) encodes a membrane protein that promotes cholesterol and phospholipid efflux from cells. Mutations in ABCA1 lead to HDL deficiency and tissue accumul...Keywords
This publication has 28 references indexed in Scilit:
- Novel approaches to treating cardiovascular disease: lessons from Tangier diseaseExpert Opinion on Investigational Drugs, 2001
- A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and AtherogenesisMolecular Cell, 2001
- The Correlation of ATP-binding Cassette 1 mRNA Levels with Cholesterol Efflux from Various Cell LinesJournal of Biological Chemistry, 2000
- ABC1 Gene Expression and ApoA-I-Mediated Cholesterol Efflux Are Regulated by LXRBiochemical and Biophysical Research Communications, 2000
- Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1Journal of Clinical Investigation, 2000
- Molecular Cloning of the Human ATP-Binding Cassette Transporter 1 (hABC1): Evidence for Sterol-Dependent Regulation in MacrophagesBiochemical and Biophysical Research Communications, 1999
- ATP-Binding Cassette Transporter A1 (ABCA1) in Macrophages: A Dual Function in Inflammation and Lipid Metabolism?Pathobiology, 1999
- Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigmCell, 1994
- Clinical, biochemical, and genetic features in familial disorders of high density lipoprotein deficiency.Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1984
- Metabolism of High-Density Lipoprotein Apolipoproteins in Tangier DiseaseNew England Journal of Medicine, 1978