Experimental myocardial infarction. I. Production of left ventricular failure by gradual coronary occlusion in intact conscious dogs

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Abstract
A new method is described for producing acute myocardial infarction in dogs, by gradually inflating a balloon cuff which has been implanted around a coronary artery. The procedure results in myocardial damage severe enough to cause left ventricular failure, yet the survival rate is high.