The Influence of Sybean Antitrypsin on the Intestinal Proteolysis of the Chick

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Abstract
The influence of a raw-soybean diet on the chicks' intestinal proteolysis was studied, in order to explain the growth-retarding effect. In chicks up to three weeks old, intestinal proteolysis was almost completely inhibited. From the 4th week proteolysis increased, approaching the normal at 6 weeks. The presence or absence of antitryptic activity was closely correlated with depressed or normal proteolytic activity. Hypertrophy of the pancreas developed in the raw soybean group, probably because of increased enzyme production to overcome the inhibitor. The chick growth retardation by antitrypsin can be explained by the unavailability of protein especially in the first three weeks of age and an increased protein requirement by stimulated pancreas.