Composition and Biosynthesis of Sterols in Some Sponges

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Abstract
1. The capacity of synthesizing sterols was investigated in the sponges Euspongia officinalis, Axinella damicornis, Geodia miilleri and two Halichondria species. It was found that the radioactive acetate administered to the sponges was utilized for the bio- synthesis of saponifiable and non-saponifiable lipids, including sterols. 2. The sterols of Geodia, Halichondria I and Eusfiongia are ;5 unsaturated. The sterol mixture of Euspongia is very complex, cholesterol being strongly predominant. 3. The sterols of Halichondria II and Axinella are nuclear saturated, though some ;7 sterols are present. 4. In Axinella a series of completely new sterols was found. Identification of them is in progress.

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