Urinary excretion of proteins in chromeplaters, exchromeplaters and referents.

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Abstract
.beta.2-Microglobulin was measured in the urine of 24 exposed chromeplaters, 27 previously exposed chromeplaters and 37 referents. The concentration of .beta.2-microglobulin and the number of elevated values (> 0.30 mg/l) was higher in the presently exposed group than in the referents. Within the presently exposed group there was a dose-effect relation between the concentration of Cr6+ in air and the number of elevated values of urinary .beta.2-microglobulin. No difference between the previously exposed chromeplaters and the referents was demonstrated regarding urinary .beta.2-microglobulin. There were no indications that the exposure could raise the excretion of albumin in urine. The results indicated an acute effect on the kidney tubules, which was reversible even in workers who had a relatively high exposure to chromic acid.