Ageing in vivo and Neuraminidase Treatment of Rabbit Erythrocytes: Influence on Half-Life as Assessed by51Cr Labelling
- 1 January 1975
- journal article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 356 (1) , 391-398
- https://doi.org/10.1515/bchm2.1975.356.1.391
Abstract
Old and young rabbit erythrocytes, separated by centrifugation, contained different respective activities of glucose-6-phosphate dehydrogenase, pyruvate kinase and acetylcholinesterase, and different quantities of stromal sialic acid. A systematic study of the survival rate of young and old erythrocytes incubated with different amounts of Vibrio cholerae neuraminidase is described. The half-life of intact old erythrocytes is significantly shorter than that of young erythrocytes with a similar sialic acid content.Keywords
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