Preparation of 3,3-diethoxypentan-2-one from the diethyl acetal of ethyl 2-oxobutyrate and (CH3)2CuLi
- 1 January 1971
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society D: Chemical Communications
- No. 20,p. 1244-1245
- https://doi.org/10.1039/c29710001244
Abstract
Reaction of Me2CuLi with the diethyl acetal of ethyl 2-oxobutyrate gives the synthetically useful methyl ketone(I) in nearly quantitative yield; similarly, acetophenone is formed in good yield from the reaction of ethyl benzoate and Me2CuLi.Keywords
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