Computer Calculation of Zinc(II)-Complex Distribution in Milk

Abstract
Computer simulations were performed to determine the distribution of zinc among some potentially important low-molecular-weight ligands (citrate, glutamate and picolinate) in both human and bovine milk. At high concentrations of picolinate, this ligand forms a neutral complex, which may facilitate intestinal absorption of the metal, but at lower levels of picolinate, zinc-citrate complexes are the predominant low-molecular-weight species.