Penicillin biosynthesis. A model for carbon–sulphur bond formation

Abstract
Oxidative decarboxylation of bis(4-carboxy-4,4′-dimethylbutyl) disulphide yields 2,2-dimethyltetra-hydrothiophen; this experiment is presented as a chemical model for the biosynthesis of the carbon–sulphur [C(2)–S(1)] bond of penicillins.

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