The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase.
Open Access
- 1 October 1992
- journal article
- abstracts
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 267 (29) , 20831-20834
- https://doi.org/10.1016/s0021-9258(19)36762-6
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunitsNature, 1992
- Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.Molecular Biology of the Cell, 1992
- Domains specifying thrombin–receptor interactionNature, 1991
- cDNA cloning and expression of a hamster α‐thrombin receptor coupled to Ca2+ mobilizationFEBS Letters, 1991
- Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activationCell, 1991
- Regulation of Polyphosphoinositide-specific Phospholipase C Activity by Purified G qScience, 1991
- G Proteins in Signal TransductionAnnual Review of Pharmacology and Toxicology, 1990
- Primary Structure and Biochemical Properties of an M 2 Muscarinic ReceptorScience, 1987
- Thrombin‐Cellular InteractionsAnnals of the New York Academy of Sciences, 1986
- A highly sensitive adenylate cyclase assayAnalytical Biochemistry, 1974