Abstract
RECENTLY, a patient with an external biliary fistula was admitted to the Montefiore Hospital in New York City. Since the opportunity to study hepatic bile extensively over a prolonged period rarely presents itself, it was decided to investigate the general characteristics of the bile, the electrolyte pattern, the lipid pattern and the excretion of certain heavy metals.‡ After the bile electrolyte and cholesterol concentrations had been found to vary within very narrow limits, the possible effect on the bile electrolytes of Diamox, a carbonic anhydrase inhibitor, and on the bile cholesterol of β-sitosterol by mouth was also investigated.Case Report . . .

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