SUSCEPTIBILITY TESTING OF PSEUDOMONAS AERUGINOSA BY THE VITEK 2 SYSTEM: A COMPARISON WITH ETEST RESULTS
- 1 February 2005
- journal article
- research article
- Published by Taylor & Francis in Acta Clinica Belgica
- Vol. 60 (1) , 3-9
- https://doi.org/10.1179/acb.2005.002
Abstract
P. aeruginona infections need accurate antimicrobial susceptibility data, as treatment mainly relies on antibiotic efficiency in debilitated patients. Vitek 2, a popular automated susceptibility testing method, was compared with Etest to assess its reliability on 150 Belgian P. aeruginonas isolates. Vitek 2 and Etest exhibited a high degree of concordance, but some discrepancies in clinical category were evident for cefepime (high minor and borderline very major error rate) and for piperacillin/tazobactam (high very major error rate). Vitek 2 appears to yield valuable information to the clinician concerning the antimicrobials amikacin, ceftazidime, ciprofloxacin and meropenem, in the setting of pseudomonas infection. For cefepime and piperacillin/tazobactam, a confirmatory testing by means of disk diffusion is worth considering.Keywords
This publication has 16 references indexed in Scilit:
- Comparison of Four Antimicrobial Susceptibility Testing Methods To Determine the In Vitro Activities of Piperacillin and Piperacillin-Tazobactam against Clinical Isolates of Enterobacteriaceae and Pseudomonas aeruginosaJournal of Clinical Microbiology, 2003
- Comparative evaluation of the VITEK 2 Advanced Expert System (AES) in five UK hospitalsJournal of Antimicrobial Chemotherapy, 2003
- Antimicrobial Susceptibility Testing of Carbapenems: Multicenter Validity Testing and Accuracy Levels of Five Antimicrobial Test Methods for Detecting Resistance in Enterobacteriaceae and Pseudomonas aeruginosa IsolatesJournal of Clinical Microbiology, 2003
- Multicentre evaluation of the VITEK 2 Advanced Expert System for interpretive reading of antimicrobial resistance testsJournal of Antimicrobial Chemotherapy, 2002
- Clinical evaluation of the Vitek automated system with cards GNS 122 and 127 and VTK-R07.01 software for antimicrobial susceptibility testing of Pseudomonas aeruginosaDiagnostic Microbiology and Infectious Disease, 2002
- Validation of the VITEK2 and the advance expert system with a collection of enterobacteriaceae harboring extended spectrum or inhibitor resistant β-lactamasesDiagnostic Microbiology and Infectious Disease, 2001
- Multicenter Evaluation of an Automated System Using Selected Bacteria That Harbor Challenging and Clinically Relevant Mechanisms of Resistance to AntibioticsEuropean Journal of Clinical Microbiology & Infectious Diseases, 2001
- Comparison of two commercial systems (Vitek and MicroScan-WalkAway) for antimicrobial susceptibility testing of Pseudomonas aeruginosa isolates from cystic fibrosis patientsDiagnostic Microbiology and Infectious Disease, 2001
- Incidence, Risk, and Prognosis Factors of Nosocomial Pneumonia in Mechanically Ventilated PatientsAmerican Review of Respiratory Disease, 1990
- Nosocomial PneumoniaChest, 1988