5‐HYDROXYTRYPTAMINE AND MYOCLONUS INDUCED BY 1,2‐DI‐HYDROXYBENZENE (CATECHOL) IN THE GUINEA‐PIG
Open Access
- 19 July 1979
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 66 (3) , 358-360
- https://doi.org/10.1111/j.1476-5381.1979.tb10837.x
Abstract
Myoclonus induced by catechol in the guinea-pig is not altered by manipulation of cerebral 5-hydroxytryptamine (5-HT). The administration of catechol does not alter brain levels of 5-HT or its metabolite 5-hydroxyindole acetic acid. This form of myoclonus therefore is not of relevance to the 5-HT-sensitive post-anoxic action myoclonus occurring in man.Keywords
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