Adenosine: A Retaliatory Metabolite or Not?
- 1 April 1990
- journal article
- research article
- Published by American Physiological Society in Physiology
- Vol. 5 (2) , 67-70
- https://doi.org/10.1152/physiologyonline.1990.5.2.67
Abstract
Adenosine has been called a "retaliatory metabolite", since its physiological actions have a common tendency to redress an imbalance between energy demand and availability. Its formation is linked directly to the net breakdown of cytosolic ATP. This hypothesis is still useful to explain much of the physiology of adenosine but is challenged by evidence for adenosine formation from extracellular ATP.Keywords
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