Mode of action of the new selective leukotriene synthesis inhibitor BAY X 1005 {(R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid} and structurally related compounds

This publication has 12 references indexed in Scilit:

• FLAP: a novel drug target for inhibiting the synthesis of leukotrienes
  Trends in Pharmacological Sciences, 1991
• Leukotrienes and Other Products of the 5-Lipoxygenase Pathway
  New England Journal of Medicine, 1990
• Involvement of calcium in the thimerosal-stimulated formation of leukotriene by fMLF in human polymorphonuclear leukocytes
  Biochemical Pharmacology, 1990
• Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
  Nature, 1990
• Identification and isolation of a membrane protein necessary for leukotriene production
  Nature, 1990
• L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor
  Canadian Journal of Physiology and Pharmacology, 1989
• Enzymes functional in the syntheses of leukotrienes and related compounds
  International Journal of Biochemistry, 1988
• Regulation of 5-lipoxygenase activity by the glutathione status in human polymorphonuclear leukocytes
  European Journal of Biochemistry, 1987
• 2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-l,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis
  Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1982
• How is the level of free arachidonic acid controlled in mammalian cells?
  Biochemical Journal, 1982