The effect of urea on the solubility of methyl p-hydroxybenzoate in aqueous sodium chloride solution

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Abstract
The effects of sodium chloride and urea, separately and together, on the solubility of methyl p-hydroxybenzoate in water have been studied. Sodium chloride decreases and urea increases the solubility. Observed and calculated “salting-out” parameters have been obtained for addition of sodium chloride to the benzoate-urea-water systems. Good agreement was observed between calculated and observed values, and the change in the “salting-out” parameters as the concentration of urea altered may indicate dipole-ion interaction between urea and sodium chloride.