Nitrogen Versatility in Bats, Bears and Man

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Abstract
The limits of nitrogen excretion and conservation by normal man continue to provoke interest for economic, anthropologic and medical reasons. Rudman et al.1 have recently shown that the maximum rate of urea synthesis is such that if man ate protein alone, he could barely meet his basal daily caloric needs, unless a chronic high protein intake induced an increase in urea synthetic capacity. Nuzum and Snodgrass2 have shown that such an increase occurs in protein-fed primates, and Snodgrass (personal communication) has suggested glucagon may be the inducer of the increase in urea-synthetic capacity. Normal man's relative rate of urea synthesis . . .