REDUCED LYMPHOCYTE COLONY FORMATION WITH AGE
- 1 January 1982
- journal article
- research article
- Vol. 49 (1) , 129-134
Abstract
The lymphocyte colony forming ability of 893 normal healthy individuals aged 17-89 was studied. The total lymphocyte count did not alter with age, but there was a decline in the colony-forming ability of cells from people with increasing age (r = 0.68, P < 0.001). This age related defect was further investigated in 11 mixing experiments using paired young and old individuals. The defect in aged individuals was due primarily to a defect in the number and/or proliferative ability of the colony-forming cells.This publication has 23 references indexed in Scilit:
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