Treatment of T prolymphocytic leukemia with allogeneic bone marrow transplantation
- 1 March 1998
- journal article
- case report
- Published by Springer Nature in Bone Marrow Transplantation
- Vol. 21 (6) , 627-628
- https://doi.org/10.1038/sj.bmt.1701127
Abstract
T prolymphocytic leukemia (T-PLL) is an unusual disease characterized by high white cell counts, older age at presentation, splenomegaly and a very aggressive clinical course. We describe a 47-year-old male with refractory T-PLL who was treated with high-dose chemoradiotherapy and allogeneic bone marrow transplantation (BMT) from an HLA-matched sibling. The transplant was complicated by both acute and chronic graft-versus-host disease (GVHD). The patient achieved complete remission and remains in remission 3 years after the transplant.Keywords
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