A new hemoglobin variant, Hb Mito [β144(HC 1)Lys → Glu], with increased oxygen affinity
Open Access
- 11 November 1985
- journal article
- Published by Wiley in FEBS Letters
- Vol. 192 (1) , 75-78
- https://doi.org/10.1016/0014-5793(85)80046-6
Abstract
A new abnormal hemoglobin, Hb Mito [β144(HC 1)Lys → Glu], with an amino acid substitution in the 2,3‐DPG pocket, was discovered in a Japanese female. This hemoglobin showed increased oxygen affinity, and decreased organic phosphate and Bohr effects, while the Hill constant n was normal.Keywords
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