HIV resistance to zidovudine: the role of pyrophosphorolysis
- 1 April 1999
- journal article
- Published by Elsevier in Drug Resistance Updates
- Vol. 2 (2) , 91-95
- https://doi.org/10.1054/drup.1999.0076
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- Mechanisms of clinical resistance by HIV-I variants to zidovudine and the paradox of reverse transcriptase sensitivityDrug Resistance Updates, 1998
- Pre-Steady-State Kinetic Characterization of Wild Type and 3‘-Azido-3‘-deoxythymidine (AZT) Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Implication of RNA Directed DNA Polymerization in the Mechanism of AZT ResistanceBiochemistry, 1997
- Single-Step Kinetics of HIV-1 Reverse Transcriptase Mutants Responsible for Virus Resistance to Nucleoside Inhibitors Zidovudine and 3-TCBiochemistry, 1997
- Analysis of HIV-2 RT mutants provides evidence that resistance of HIV-1 RT and HIV-2 RT to nucleoside analogs involves a repositioning of the template-primerJournal of Molecular Biology, 1997
- Locations of Anti-AIDS Drug Binding Sites and Resistance Mutations in the Three-dimensional Structure of HIV-1 Reverse TranscriptaseJournal of Molecular Biology, 1994
- Sensitivity of HIV-1 Reverse Transcriptase and Its Mutants to Inhibition by Azidothymidine TriphosphateBiochemistry, 1994
- Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine.Proceedings of the National Academy of Sciences, 1992
- Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytesAIDS, 1991
- Characterization of Reverse Transcriptase Activity and Susceptibility to Other Nucleosides of AZT‐Resistant Variants of HIV‐1Annals of the New York Academy of Sciences, 1990
- Multiple Mutations in HIV-1 Reverse Transcriptase Confer High-Level Resistance to Zidovudine (AZT)Science, 1989