Graves' Ophthalmopathy: Etiology and Treatment
- 1 March 1975
- journal article
- research article
- Published by Taylor & Francis in Hospital Practice
- Vol. 10 (3) , 125-134
- https://doi.org/10.1080/21548331.1975.11946413
Abstract
The varied and unpredictable ophthalmic manifestations of Graves' disease are ascribed to an autoimmune reaction in which components of a pathogenic “stew” —thyroglobulin (Tg), anti-Tg antibodies, Tg-anti-Tg complexes, and sensitized lymphocytes—bind with and damage extraocular muscle membranes. The rationale of supervoltage orbital irradiation is discussed, as is patient response.Keywords
This publication has 4 references indexed in Scilit:
- Binding of Thyroglobulin and Thyroglobulin-Antithyroglobulin Immune Complex to Extraocular Muscle MembraneEndocrinology, 1974
- Graves' Ophthalmopathy Following External Neck Irradiation for Nonthyroidal Neoplastic DiseaseJournal of Clinical Endocrinology & Metabolism, 1973
- Supervoltage Orbital Radiotherapy for Graves' Ophthalmopathy1Journal of Clinical Endocrinology & Metabolism, 1973
- Measurements by Competitive Binding Radioassay of Serum Anti-Microsomal and Anti-Thyroglobulin Antibodies in Graves' Disease and other Thyroid Disorders1Journal of Clinical Endocrinology & Metabolism, 1971