3D QSAR studies of the interaction between β-tubulin and microtubule stabilizing antimitotic agents (MSAA). A combined pharmacophore generation and pseudoreceptor modeling approach applied to taxanes and epothilones
- 1 May 2003
- journal article
- Published by Elsevier in Il Farmaco
- Vol. 58 (5) , 357-361
- https://doi.org/10.1016/s0014-827x(03)00052-1
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Refined structure of αβ-tubulin at 3.5 Å resolution 1 1Edited by I. A. WilsonJournal of Molecular Biology, 2001
- Metastatic colorectal cancerCurrent Treatment Options in Oncology, 2001
- The Epothilones, Eleutherobins, and Related Types of MoleculesCurrent Pharmaceutical Design, 2001
- Ovarian CancerThe Oncologist, 2001
- The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: Curative effects of desoxyepothilones B and F against human tumor xenografts in nude miceProceedings of the National Academy of Sciences, 2001
- Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cellsLeukemia, 2001
- A model for the taxol (paclitaxel)/epothilone pharmacophoreBioorganic & Medicinal Chemistry Letters, 1996
- Peripheral neuropathy from taxol and cisplatin combination chemotherapy: Clinical and electrophysiological studiesAnnals of Neurology, 1994
- Coping with toxicities of docetaxel (TaxotereTM)Annals of Oncology, 1993
- TaxolAnti-Cancer Drugs, 1991