Ca2+-Dependent Binding of Synthetic Peptides Corresponding to Some Regions of Troponin-I to Troponin-C1

Abstract
We have chemically synthesized two peptides corresponding to the binding regions of troponin-I for troponin-C. Electrophoretic analysis has shown that one of the two peptides binds Ca2+-dependently to troponin-C and the other Ca2+-independ-ently. The biological significance of the results is discussed. The interaction of the peptides with calmodulin was different from that with troponin-C.

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