Deoxythymidine Metabolism in Avian Erythroid Cells
Open Access
- 1 November 1972
- journal article
- Published by The Company of Biologists in Journal of Cell Science
- Vol. 11 (3) , 777-784
- https://doi.org/10.1242/jcs.11.3.777
Abstract
The ability of dividing and non-dividing cells of the avian erythropoietic series to phosphorylate [3H] deoxythymidine and [3H]uridine has been studied. Enzyme levels of deoxythymidine kinase were also assayed. Both dividing and immature non-dividing erythroid cells phosphorylated uridine to uridine triphosphate (UTP). However, only cells able to synthesize DNA could phosphorylate deoxythymidine to the triphosphate; also these cells were the only ones to show detectable deoxythymidine kinase activities.Keywords
This publication has 10 references indexed in Scilit:
- DNA Polymerase in Avian Erythroid CellsJournal of Cell Science, 1972
- Dna Synthesis in Purified Populations of Avian Erythroid CellsJournal of Cell Science, 1972
- Practical methods for the routine chemical synthesis of 32P-labelled nucleoside di- and triphosphatesBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1970
- The effect of endogenous pools of thymidylate on the apparent rate of DNA synthesisExperimental Cell Research, 1969
- Thymidine triphosphate content of regenerating rat liverBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1969
- The phosphorylation of thymidine by oocytes and eggs of Xenopus laevis DaudinBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1969
- Phosphorylation of tritiated thymidine by L929 mouse fibroblastsExperimental Cell Research, 1969
- Messenger RNA in avian erythroblasts at the transcriptional and translational levels and the problem of regulation in animal cellsJournal of Cellular Physiology, 1968
- Synthesis of chicken hemoglobins during erythrocyte differentiationBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1967
- Patterns of RNA metabolism in a differentiated cell: a rapidly labeled, unstable 60S RNA with messenger properties in duck erythroblasts.Proceedings of the National Academy of Sciences, 1966